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  • EXAMPLES Example 1 Zoledronic Acid 4 mg100 mLIngredientAmount kg per 1000 LZoledronic acid monohydrate0. Mannitol is added and dissolved under stirring. Decisions of the ICSC on Post Adjustment issues ICSC 85th session At its ongoing 85th session, the International Civil Service Commission (ICSC) has taken the.
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  • The water layers were combined, and ethyl acetate 22 l was added, and then acetic acid was added drop by drop to reach a pH of about 8 under cooling. The effective sterilization time dwell time may be from about 15 minutes up to about 3 hours, conveniently from about 15 minutes to about 2 hours, e. Decisions of the ICSC on Post Adjustment issues ICSC 85th session At its ongoing 85th session, the International Civil Service Commission (ICSC) has taken the.
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  • More preferred is 1. A pharmaceutical product comprises a container containing a bisphosphonate solution, in which at least the internal surface of the container comprises a plastic.
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  • The results of powder X-ray diffraction analysis of this wet crystal are shown below. It also supplies copies of records and other papers. Discussion of patent issues focusing on the biotechnology and pharmaceutical industries.
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The human human recovery from five non washed vials is determined in human spike controls. It has now been found that bisphosphonate solutions may be formulated for man term storage in containers comprising polymeric materials which containers do not chemically interact with the bisphosphonate assignment patent and assignment patent may be conveniently terminally sterilised.

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  • Preferably, however, the container is made of plastic material and does not comprise a glass outer shell. After the solution was kept standing at room temperature overnight, water 20 ml was added, followed by ultrasonication. Decisions of the ICSC on Post Adjustment issues ICSC 85th session At its ongoing 85th session, the International Civil Service Commission (ICSC) has taken the.
  • However, WO 0222136 does not include any teaching as to how, when or if the product is sterilised. Decisions of the ICSC on Post Adjustment issues ICSC 85th session At its ongoing 85th session, the International Civil Service Commission (ICSC) has taken the.
  • Such antioxidants include, for example, sulfites, ascorbic acid and -tocopherol. Prepared by and for policy makers, leaders of public and private sector research, tech transfer professionals, licensing executives, and scientists, this online.
  • More preferred bisphosphonates for use in the invention are Disodium-3-amino-1-hydroxy-propylidene-1, 1-bisphosphonate pentahydrate pamidronic acid and 2- imidazol-1yl -1-hydroxyethane-1, 1-diphosphonic acid zoledronic acid or pharmacologically acceptable salts thereof. It also supplies copies of records and other papers. The Federal Circuit does not have subject matter jurisdiction over state law claims seeking a declaration that an assignment of patent rights was invalid.
  • The drug substance pamidrionic acid disodium salt pentahydrate is added and dissolved under stirring. Decisions of the ICSC on Post Adjustment issues ICSC 85th session At its ongoing 85th session, the International Civil Service Commission (ICSC) has taken the.

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